News

Scientists reveal that glucose, an essential cellular fuel that powers immune cells, also aids in T cells’ internal communication and boosts their cancer-fighting properties.

Researchers from the Japan Advanced Institute of Science and Technology, in collaboration with Daiichi Sankyo and the University of Tsukuba, have developed a bacteria-based cancer therapy that does not rely on the immune system.

Researchers have shown that a transcriptional repressor called Gfi1, or growth factor independent-1, is a key regulator of the subset formation of exhausted CD8+ T cells and may offer a key to reducing exhaustion.

Particularly difficult DNA repair cases are now known to be transported to the inner edge of the nucleus, to be fixed by a secondary set of DNA repair enzymes.

Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body.

A two-drug combination for treating advanced kidney cancer had sustained and durable clinical benefit in more than five years of follow-up.

Targeting metabolism in tumors can enable the immune system to kill liver cancer cells, a new study has found.

New research defines four different immunologic subtypes of recurrent ovarian cancers and describes how those subtypes are related to a key genomic characteristic of host tumors.

Researchers have identified how cancer cells exploit ordinary metabolic processes to manipulate immune cells, supporting their growth and survival.

A US study of 300,000 prostate cancer patients found that 1 in 6 men diagnosed with Grade Group 1 cancer had higher-risk disease. Over 18,000 cases had clinical features suggesting surgery or radiation was needed.