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Study Challenges Assumption That Warfarin Raises Brain Bleed Risk After Falls

The researchers conducted a one-year investigation at two Level I trauma centers in South Florida, analyzing data from 2,686 adults aged 65 and older admitted after fall-related head injuries.
Floss between a tooth and the gum in a bubble surrounded by antibodies, representing a new method for vaccine delivery.
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Dental Floss Could Be Used To Administer Future Vaccines

Researchers have demonstrated a novel vaccine delivery method in an animal model, utilizing dental floss to administer the vaccine to the tissue between the teeth. The new technique stimulated the production of antibodies in mucosal surfaces.
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Vitamin D Found To Reduce Liver Damage Through TXNIP Activation in Mice

Researchers from Chungnam National University examined how vitamin D influences liver repair mechanisms in chronic liver disease.
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AI Model Predicts How Efficiently mRNA Sequences Will Produce Proteins

A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types.
A close-up of a syringe drawing liquid from a vaccine vial.
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Method Predicts Vaccination Levels Without Accurate or Timely Vaccination Data

Researchers at Penn State and the World Health Organization have developed a method to predict measles vaccination levels using routinely collected clinical data on suspected measles cases.
Interactions between a cancer cell and immune cells, illustrating immunotherapy principles.
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Hormone Suppresses Immune Cells, Allowing Cancer Cells To Avoid Detection

Researchers have discovered how a hormone interacts with a receptor on the surface of immune cells to shield cancer cells from the body’s natural defenses.
A female scientist in PPE holding up a red pill, representing drug discovery.
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Guselkumab Outperforms Existing Crohn’s Disease Treatments in Trials

Guselkumab, a medication with a mechanism of action that is new to inflammatory bowel disease (IBD) treatment, outperformed an established standard of care in promoting intestinal healing and symptom relief.
Gloved hands (blue) ready to inject a shoulder.
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Therapeutic Vaccine for Chronic Hepatitis B Begins Clinical Trials In Patients

The candidate, TherVacB, developed through research led by Helmholtz Munich, is now being evaluated in a multi-site phase 1b/2a trial. The first patient was enrolled in June 2025.
A close-up of a persons arm connected to an IV drip receiving cell therapy.
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Cellular Immunotherapies Tendency to Self-Destruct Explained

Researchers have discovered that immune cells are the unexpected source of a protein called FAS-ligand, which has undermined the cancer-fighting ability of engineered cell therapies.
Single strands of RNA against a dark blue background.
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RNA Therapeutics Add to Drug Arsenal Against Hepatitis B

Scientists report that a class of drugs, called RNA interference (RNAi) therapeutics, represent a major advancement in the treatment of chronic HBV infections, expanding treatment strategies.
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