News

White sharks nearly vanished during the last Ice Age, rebounding into distinct global populations. Yet mitochondrial and nuclear DNA tell conflicting stories. A 150-genome study ruled out migration and female philopatry as causes.

Researchers have traced a source of poor tendon healing and retrained epitenon cells for a better recovery from surgery.

University of Birmingham researchers have uncovered a new fat regulation mechanism involving internal FFA4 receptors near lipid droplets in fat cells. These receptors act as built-in sensors, triggering feedback to slow fat breakdown.

Scientists reveal that glucose, an essential cellular fuel that powers immune cells, also aids in T cells’ internal communication and boosts their cancer-fighting properties.

Researchers have developed a machine learning model that enables early prediction of organoid quality, thus progressing organoid research and regenerative medicine.

A study led by scientists at Case Western Reserve University used stem cells created from ALS patients to target a specific gene as a kind of shut-off valve for what stresses nerve cells – and it worked.

New research shows that cells in high-energy-demanding tissues respond to mitochondrial dysfunction through a sophisticated metabolic response that alters cell identity.

Researchers found that two evolutionary changes to the ADSL enzyme, one amino acid substitution and a regulatory RNA variant, likely reduced enzyme activity in the human brain.

Researchers have shown that a transcriptional repressor called Gfi1, or growth factor independent-1, is a key regulator of the subset formation of exhausted CD8+ T cells and may offer a key to reducing exhaustion.

University of Michigan researchers found that sugar metabolism in neurons influences whether axons degrade or survive after injury. In fruit flies, disrupted metabolism activated DLK and suppressed SARM1 to promote axon resilience.