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Illustration of microscopic cancer cells.
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Scientists Uncover Cancer-Fighting Power of Plant Virus

Researchers have taken a closer look at how the cowpea mosaic virus (CPMV), unlike other plant viruses, is uniquely effective at activating the body’s immune system to recognize and attack cancer cells.
Fluorescent microscopy of zebrafish liver tumor highlighting KRAS activity and DNA damage.
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Blocking Minor Splicing Slows Tumour Growth in Cancer Models

A WEHI-led study reveals that blocking minor splicing – an RNA process critical for cell division – reduces tumour growth in models of liver, lung and gastric cancers. The approach selectively affects cancer cells reliant on KRAS mutations.
Interactions between a cancer cell and immune cells, illustrating immunotherapy principles.
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Hormone Suppresses Immune Cells, Allowing Cancer Cells To Avoid Detection

Researchers have discovered how a hormone interacts with a receptor on the surface of immune cells to shield cancer cells from the body’s natural defenses.
Illustration of cancer cells dividing to form more cancer cells.
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Scientists Simulate Cancer Cell Behavior

Researchers at the University of Maryland School of Medicine invent software fueled by genomics into mathematical models to predict cancer cell behavior.
Illustration of red microscopic cancer cells.
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Uncovering How Prostate Cancer Becomes Deadly

In a significant advancement for prostate cancer research, a first-of-its kind study led by Emory researchers uncovered how the disease transforms into its most lethal form — and identified a promising new treatment strategy.
A combination of drugs on a target, representing drug screening.
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Genetic Screening Reveals Drug Combination for Hard-To-Treat Cancers

Using CRISPR gene editing, researchers revealed a combination of therapies that showed promise in treating cancer in preclinical models. The study could help guide development of new therapies for some treatment-resistant cancers.
A red and blue drug pill split in half with a model of a molecule in the middle.
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Microscopic Containers Enable Precision Drug Delivery

By encapsulating magnetic particles in lipid vesicles, researchers have created microscopic drug delivery containers which magnetic fields can steer to precise locations in the body. The result has promise for precision medicine and cancer treatment.
Firefighters in full gear using a hose to extinguish a burning structure during an emergency response.
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Firefighter Blood Study Reveals Early Genetic Signs of Health Risk

Researchers found that PFAS exposure in firefighters alters microRNAs tied to cancer and other diseases. Analyzing blood samples, they linked specific PFAS to miRNA changes connected to cancer, neurological and autoimmune pathways.
Illustration of a tumor, with blood supply, and its microenvironment.
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Reshaping the Tumor Environment To Boost Cancer Treatments

Scientists at Sanford Burnham Prebys have demonstrated that blocking macropinocytosis reshapes the tumor microenvironment, making it less fibrous and allowing more access to immune cells.
Graphic of T cells (orange) attacked a cancer cell.
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AI-Designed Proteins Reprogram Immune Cells To Target Cancer

A new method can produce custom-designed proteins in just 4-6 weeks, enabling the body's immune system to arm T cells and attack and kill cancer cells.
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