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A top-down view of a jar of sweets.
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How Sweet Receptors Detect Sweeteners

Scientists used structural biology approaches to gain insight into how sweet taste receptors detect sweeteners, guiding the design of better sweeteners.
Illustration of microscopic blue iridescent cells.
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Reducing Inflammation To Prevent Kidney Damage in Lupus

Researchers are developing a new approach to preventing lupus nephritis – improving the health and function of the cells that line the kidney blood vessels, to prevent immune cells from leaking into kidney tissue and damaging it.
Neurons fire signals between each other, illustrating neurodevelopment.
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Decrease in Ribosomes Detected During Neurodevelopment

Researchers have identified a stage of neurodevelopment where differentiating neural cells produce fewer ribosomes, potentially offering an explanation for some neurodevelopmental disorders.
A broken strand of DNA, which may be repaired by a secondary DNA repair tool box.
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Cells Have a Second DNA Repair Toolbox

Particularly difficult DNA repair cases are now known to be transported to the inner edge of the nucleus, to be fixed by a secondary set of DNA repair enzymes.
Illustration of brain with certain areas illuminating colors, indicating psyschedelics.
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Psychedelics and Non-Hallucinogenic Analogs Activate the Same Pathway, Differently

Researchers found that non-hallucinogenic versions of psychedelic drugs promote neuroplasticity through the same biochemical pathway as psychedelics. However, they don’t activate genes long thought to be key players in that process.
A plastic model of human lungs, with airways and alveoli visible.
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Lung-on-a-Chip Helps Unravel Responses to Respiratory Viruses

A lung-on-a-chip system emulates different regions of human lungs to help researchers understand respiratory infections.
Lipids align in the cell membrane, packed closely together.
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Researchers Identify Biophysical Rules Governing Cell Membrane Behavior

The erratic behavior of cell membranes could be explained by unified biophysical laws relating to how lipids are packed into the membrane, which were identified at the nanoscale.
A person's midsection, with organs illustrated in blue. The pancreas is highlighted in red, symbolising immune targets.
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Sugar "Coat" Protects Cells Typically Destroyed in Type 1 Diabetes

Cancer cells coat themselves in a sugar to avoid the immune system, and now research has shown that dressing pancreatic beta cells in the same sugar enables the immune system to tolerate them.
Diagram of how the IGFL2 gene is only found in humans and primates and how the gene contributes to the development of rheumatoid arthritis.
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Study Reveals What Fuels Rheumatoid Arthritis Inflammation

Researchers have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis.
The image shows eIF2A at the centrosome (white) of cancerous cells.
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The “Sat-Nav” Protein That Helps Cancer Cells Spread

Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body.
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