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Missing Messenger RNA Could Be Key to New Immunotherapies
Researchers identified messenger RNA that is missing in pediatric high-grade glioma tumors but not in normal brain tissues. Preclinical research indicates that these RNA fragments can make difficult-to-treat tumors more responsive to immunotherapy.

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A Fading Sense of Smell May Be the Earliest Sign of Alzheimer's Disease
In early Alzheimer's disease, the brain's immune system fatally attacks neuronal fibers crucial for the perception of odors.

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Tiny Pond Worms Could Replace Lab Rats in Brain Research
University of Reading scientists found that flatworms (planaria) respond to antipsychotic drugs like rodents do, suggesting they could serve as ethical, low-cost models for psychiatric research.

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Antibiotic Could Lower Heart Attack Risk for People With Type 2 Diabetes
Researchers showed that blocking SEC61B activity with an antibiotic – anisomycin – reduced platelet clumping in human samples and animal models, offering new opportunities for treating people with type 2 diabetes at risk of heart attack and stroke.

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Scientists Take First Step to Creating Human Eggs and Sperm in Lab
Wyss Institute and Harvard Medical School scientists have developed the first in vitro system that initiates human meiosis from stem cells, bypassing the primordial germ cell stage. The team induced gamete development.

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Potential Mechanism of Breast Cancer Resistance Identified
Disruption to a cellular stress response system involving the JNK pathway allows estrogen receptor-positive breast cancer cells to evade treatment.

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How Hormone Therapy Impacts the Athletic Performance of Transgender Women
A new study from Loughborough University has explored how gender-affirming hormone therapy affects the athletic performance of transgender women athletes.

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Global Plastics Treaty Negotiations End With No Deal for Second Time
Delegates from 184 countries arrived in Geneva this week to resolve outstanding disagreements on limiting plastic production, managing existing plastic products and supporting the implementation of a plastics treaty in developing countries.

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Probiotics for Preterm Babies Lowered Antibiotic Resistant Bacteria in Gut
Preterm babies with very low birth weight who received a probiotic alongside antibiotics had fewer multidrug-resistant bacteria and a more typical gut microbiome.

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Antarctica’s Changing Landscape Underscores Need for Coordinated Action, Say Researchers
In the face of growing global pressures, a new report from Securing Antarctica’s Environmental Future, including University of Adelaide researchers, highlights the opportunity to strengthen and future-proof Antarctic governance.
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