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Women living in US counties with persistently low rates of cervical cancer screening face nearly double the risk of being diagnosed with the disease, particularly at a late stage.

Researchers at The Hong Kong Polytechnic University developed two AI models – MMgSN-Net and PGMGVCE – to create virtual contrast-enhanced MRI scans for nasopharyngeal carcinoma using non-contrast images.

In the phase 2 SunRISe-1 trial, TAR-200, a slow-release intravesical device delivering gemcitabine, eliminated tumors in 82% of high-risk NMIBC patients unresponsive to BCG therapy. Nearly half remained cancer-free after 12 months.

Releasing a newly-identified molecular brake that hinders the ability of T cells to attack tumors could supercharge immunotherapy.

New research has revealed how cancer cells enter and survive within bone marrow fibroblasts to evade anti-cancer drugs.

Researchers have shown that patients with vocal fold lesions and laryngeal cancer can be distinguished through acoustic features of the voice. AI systems could use this to help triage patients at risk for laryngeal cancer based on their voice.

A cancer drug could enhance how patients respond to chemotherapy even in treatment-resistant tumours. In preclinical models, it has already shown promise in making chemotherapy-resistant cancers more responsive to therapy.

A new AI model can design and optimize drug candidate molecules tailored to a protein’s structure alone – without needing prior information about binding molecules.

Researchers found that MYCN located on extra-chromosomal DNA enables some neuroblastoma cells to enter a dormant, therapy-resistant state. Combining chemotherapy with drugs targeting senescent cells removed aggressive and dormant cells in models.

New research has uncovered how different types of gut bacteria feed on a prominent dietary antioxidant found in mushrooms, shedding light on molecular pathways that could form a cancer drug target.